هل يمكننا إعادة بناء الدماغ؟ | شون سيمونيني | TEDxBoston Salon

ظلت الأمراض التنكسية العصبية، وإصابات الدماغ الرضية، والسكتات الدماغية، والتدهور المرتبط بالعمر، تُعتبر دائمة لأن الدماغ يملك قدرة محدودة على تكوين خلايا عصبية جديدة. في محاضرة TEDxBoston Salon، يطرح شون سيمونيني، المؤسس المشارك والرئيس التنفيذي لشركة Sequel Neuroscience، فكرة أن زرع خلايا عصبية جديدة في الدماغ قد يعكس جزءا من هذا الضرر. ويتتبع العرض علاجات استبدال الخلايا، من التجارب المبكرة على مرض باركنسون إلى الأبحاث الحالية.

• لماذا كان يُعتقد أن تلف الدماغ لا رجعة فيه
• علاجات استبدال الخلايا من تجارب باركنسون المبكرة إلى الأبحاث الحالية
• استعادة النسيج الدماغي المفقود بدلا من الاكتفاء بالحفاظ على ما تبقى

NOTE FROM TED: Research discussed in this talk remains an ongoing field of study. TEDx events are independently organized by volunteers. The guidelines we give TEDx organizers are described in more detail here: http://storage.ted.com/tedx/manuals/tedx_content_guidelines.pdf When neurons die, our brains have little capacity to make new ones. This has meant that neurodegenerative conditions, traumatic brain injuries, strokes, and age-related decline have all been considered permanent and irreversible. Sean Simonini learned this the hard way, but sees hope in our ability to reverse this damage by transplanting new neurons into the brain. He traces how cell replacement therapies, from early trials in Parkinson’s to cutting edge science, are beginning to break the long-held belief that damage to the brain could never be undone. He argues that neurology is shifting from preserving what is left, to restoring what was lost, and asks what this means when new cells become a part of us. Sean Simonini is a Co-Founder & CEO of Sequel Neuroscience which is working on regenerative therapies for stroke, ALS, and other brain conditions. Previously, he was a researcher at the University of California, San Francisco and Harvard University, studying stem cell biology and neurodevelopment. He also led several nonprofits to grow the Boston biotech ecosystem, support public education, and address food insecurity. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx