Peut-on reconstruire le cerveau ? | Sean Simonini | TEDxBoston Salon

Les maladies neurodégénératives, les traumatismes crâniens, les AVC et le déclin lié à l'âge ont longtemps été considérés comme irréversibles, car le cerveau crée peu de nouveaux neurones. Lors de cette intervention TEDxBoston Salon, Sean Simonini, cofondateur et PDG de Sequel Neuroscience, évoque la possibilité de réparer une partie de ces lésions en greffant de nouveaux neurones dans le cerveau. Il retrace les thérapies de remplacement cellulaire, des premiers essais sur la maladie de Parkinson aux recherches actuelles.

• Pourquoi les lésions cérébrales étaient jugées irréversibles
• Thérapies de remplacement cellulaire, de Parkinson à la recherche actuelle
• Restaurer plutôt que seulement préserver le tissu cérébral

NOTE FROM TED: Research discussed in this talk remains an ongoing field of study. TEDx events are independently organized by volunteers. The guidelines we give TEDx organizers are described in more detail here: http://storage.ted.com/tedx/manuals/tedx_content_guidelines.pdf When neurons die, our brains have little capacity to make new ones. This has meant that neurodegenerative conditions, traumatic brain injuries, strokes, and age-related decline have all been considered permanent and irreversible. Sean Simonini learned this the hard way, but sees hope in our ability to reverse this damage by transplanting new neurons into the brain. He traces how cell replacement therapies, from early trials in Parkinson’s to cutting edge science, are beginning to break the long-held belief that damage to the brain could never be undone. He argues that neurology is shifting from preserving what is left, to restoring what was lost, and asks what this means when new cells become a part of us. Sean Simonini is a Co-Founder & CEO of Sequel Neuroscience which is working on regenerative therapies for stroke, ALS, and other brain conditions. Previously, he was a researcher at the University of California, San Francisco and Harvard University, studying stem cell biology and neurodevelopment. He also led several nonprofits to grow the Boston biotech ecosystem, support public education, and address food insecurity. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx