¿Podemos reconstruir el cerebro? | Sean Simonini | TEDxBoston Salon

Las enfermedades neurodegenerativas, las lesiones cerebrales traumáticas, los accidentes cerebrovasculares y el deterioro asociado a la edad se han considerado durante mucho tiempo permanentes, porque el cerebro apenas puede generar neuronas nuevas. En esta charla de TEDxBoston Salon, Sean Simonini, cofundador y CEO de Sequel Neuroscience, plantea que trasplantar neuronas nuevas al cerebro podría revertir parte de ese daño. Repasa las terapias de reemplazo celular, desde los primeros ensayos en la enfermedad de Parkinson hasta la investigación actual.

• Por qué el daño cerebral se consideraba irreversible
• Terapias de reemplazo celular desde los primeros ensayos en Parkinson
• Restaurar el tejido perdido en lugar de solo preservarlo

NOTE FROM TED: Research discussed in this talk remains an ongoing field of study. TEDx events are independently organized by volunteers. The guidelines we give TEDx organizers are described in more detail here: http://storage.ted.com/tedx/manuals/tedx_content_guidelines.pdf When neurons die, our brains have little capacity to make new ones. This has meant that neurodegenerative conditions, traumatic brain injuries, strokes, and age-related decline have all been considered permanent and irreversible. Sean Simonini learned this the hard way, but sees hope in our ability to reverse this damage by transplanting new neurons into the brain. He traces how cell replacement therapies, from early trials in Parkinson’s to cutting edge science, are beginning to break the long-held belief that damage to the brain could never be undone. He argues that neurology is shifting from preserving what is left, to restoring what was lost, and asks what this means when new cells become a part of us. Sean Simonini is a Co-Founder & CEO of Sequel Neuroscience which is working on regenerative therapies for stroke, ALS, and other brain conditions. Previously, he was a researcher at the University of California, San Francisco and Harvard University, studying stem cell biology and neurodevelopment. He also led several nonprofits to grow the Boston biotech ecosystem, support public education, and address food insecurity. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx